ONE OF MY TEAM EXPLAINS FIBROCYSTIC
CHANGES IN THE BREAST
This e-mail was copied to me. It was a reply
to someone who contacted me.
As busy as this pathologist is, she is supporting
the work I am attempting to accomplish.
"Dear _______,
I'll try to explain what fibrocystic changes are,
but if I am not clear just let me know and I'll try again.
Our breast is made of ducts (think of hoses) and
these ducts are covered by a thin layer of cells (only two). These cells
are in charged and programmed to make milk during pregnancy, but when there
is no pregnancy they can still produce some fluid.
If the hose (our ducts) gets too much water pressure
and the exit hole is too small; the hose gets dilated or distended. The
same thing happens to our ducts, when they produce too much fluid, they
dilate and form cysts. Now, Fibrocystic changes are primarily dilated ducts
(hoses) full of fluid that can be aspirated and the cyst collapses. Sometimes,
the two cell layer that covers the ducts may increase under a variety
of stimulus (estrogens) and then instead of 2 cell layers, there may be
3, 4 or more.
We look at those cells carefully, to make
sure there is no atypia, what means that the normal cell gets a bit
unhappy and have a larger nucleus.
The "Fibrous" means deposits of more dense breast
tissue and change because it is a change from what was normal. It is a
benign change, and the most common one in young women. It is understandable
that you are worried since you have a strong family history of cancer,
but remember that does not mean that you will get cancer for sure.
If it will make you feel better. . .You can always
send (the slides/biopsy) them to me at:
Maria J. Merino, M.D.,
National Cancer Institute, Laboratory of
Pathology, Bldg. 10, Room 2N212. Bethesda,
MD, 20892
If you want, I can request the material, you will
just need to tell me
which hospital you had the procedure done. And,
there is no charge because
we are the government. (Your tax dollars at work).
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